Premium
Synthesis of the 7‐deaza and 5‐aza‐7‐deaza purine analogs of the antiherpes agent 9‐[(1,3‐dihydroxy‐2‐propoxy)methyl]guanine (DHPG)
Author(s) -
Mcgee Danny P. C.,
Martin John C.,
Verheyden Julien P. H.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220444
Subject(s) - chemistry , purine , guanine , purine analogue , combinatorial chemistry , stereochemistry , organic chemistry , biochemistry , enzyme , nucleotide , gene
Synthesis of 2‐amino‐7‐[(1,3‐dihydroxy‐2‐propoxy)methyl]pyrrolo[2,3‐ d ]pyrimidin‐4‐one (3) a 7‐deaza purine analogue and 2‐amino‐8‐[(1,3‐dihydroxy‐2‐propoxy)methyl]imidazo[1,2‐ a]‐s ‐triazin‐4‐one (4) a 5‐aza‐7‐deaza purine analogue of DHPG (2) are reported.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom