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Synthesis and X‐Ray crystal structure of a 2,4,5‐trisubstituted 1,2,4‐triazolin‐3‐one
Author(s) -
Madding Gary D.,
Smith David W.,
Sheldon Robert I.,
Lee B.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220440
Subject(s) - chemistry , x ray , crystal structure , combinatorial chemistry , stereochemistry , crystallography , nuclear physics , physics
The synthesis and x‐ray crystal structure of BMY 13754, a 1,2,4‐triazolin‐3‐one under clinical evaluation as an antidepressant agent, is described. Several synthetic strategies are discussed.