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Non‐steroidal antiinflammatory agents. 3 . Synthesis of 3‐hydroxy‐3‐hydroxyphenyl‐2,4‐dioxo‐1,2,3,4‐tetrahydroquinolines
Author(s) -
Faber Kurt,
Steininger Heinz,
Kappe Thomas
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220431
Subject(s) - chemistry , phenols , condensation , stereochemistry , combinatorial chemistry , organic chemistry , thermodynamics , physics
The acid‐catalyzed condensation of quinisatines 5a‐c or their aminals 4a‐c with phenols 6a‐i led to a number of 3‐hydroxy‐3‐hydroxyphenyl‐2,4‐dioxo‐1,2,3,4‐tetrahydroquinolines 7a‐s which were considered as potential antiinflammatory agents.