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A regiospecific synthesis of 1‐methylamino‐6‐fluoro‐7‐(4‐methylpiperazin‐1‐yl)‐1,4‐dihydro‐4‐oxoquinoline‐3‐carboxylic acid
Author(s) -
Chu Daniel T. W.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220421
Subject(s) - chemistry , carboxylic acid , medicinal chemistry , organic chemistry
Abstract An efficient and regiospecific synthesis of 1‐methylamino‐6‐fluoro‐7‐(4‐methylpiperizin‐1‐yl)‐1,4‐dihydro‐4‐oxoquinoline‐3‐carboxylic acid ( 3 ) via an intramolecular nucleophilic displacement cyclization reaction is reported.