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The synthesis and chemistry of some bis‐aziridinylketones and their spectral study
Author(s) -
Lin TayYean,
Kingsbury Charles A.,
Adelfang Jules,
Cromwell Norman H.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220417
Subject(s) - chemistry , ketone , alkyl , nmr spectra database , medicinal chemistry , spectral properties , spectral line , primary (astronomy) , stereochemistry , organic chemistry , computational chemistry , physics , astronomy
The synthesis and spectral characteristics of certain bis(1‐alkyl‐3‐phenyl‐2‐aziridinyl)ketones are reported. The reactions of 1,2,4,5‐tetrabromo‐1,5‐diphenyl‐3‐pentanone ( 2 ) with primary amines are assumed to have a mechanism similar to that of a simple dibromo‐ketone. The so‐called cis, cis ‐ or trans, trans ‐configurations of the bis‐aziridinylketones were determined by 1 H and 13 C nmr spectra.
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