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Synthesis of 2‐deamino‐ and 2‐deamino‐2‐nitroactinomycin D
Author(s) -
Sehgal Raj K.,
Sengupta Sisir K.,
Dieter R. Karl
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220309
Subject(s) - chemistry , stereochemistry
A single step synthesis of 2‐deaminoactinomycin D ( 3a ) and 2‐deamino‐2‐nitroactinomycin D ( 2a ) arising from actinomycin D ( 1a, AMD ) is reported. Structural confirmation was made by nmr, ir and chemical conversion to known materials.
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