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Use of hypervalent iodine oxidation for the C (3)‐hydroxylation of chromone, flavone and α‐naphthoflavone
Author(s) -
Moriarty Robert M.,
Prakash Om,
Musallam H. A.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220275
Subject(s) - chemistry , chromone , hypervalent molecule , hydroxylation , iodobenzene , iodine , organic chemistry , methanol , potassium hydroxide , hydrolysis , alcohol , medicinal chemistry , catalysis , enzyme
C (3)‐Hydroxylation of chromone (1a) , flavone (1b) and α‐naphthoflavone (4) via acid‐catalysed hydrolysis of the corresponding β‐methoxy‐α‐hydroxydimethylacetals (2a, 2b , and 5) formed by iodobenzene diacetate‐potassium hydroxide methanol oxidation is described.
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