The preparation of phenacylpyrazoles, acylpyrazoles, imidazolylisoxazoles and imidazolylpyrazoles from c(α)‐dianions of oximes, phenylhydrazones and acylhydrazones | Zendy

Huff Ann M. | Zendy; Hall Howard L. | Zendy; Smith Melanie J. | Zendy; O'Grady Sheila A. | Zendy; Waters Frank C. | Zendy; Fengl Richard W. | Zendy; Welsh Jeffery A. | Zendy; Beam Charles F. | Zendy

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The preparation of phenacylpyrazoles, acylpyrazoles, imidazolylisoxazoles and imidazolylpyrazoles from c(α)‐dianions of oximes, phenylhydrazones and acylhydrazones

Author(s) -

Huff Ann M.,

Hall Howard L.,

Smith Melanie J.,

O'Grady Sheila A.,

Waters Frank C.,

Fengl Richard W.,

Welsh Jeffery A.,

Beam Charles F.

Publication year - 1985

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570220259

Subject(s) - lithium diisopropylamide , chemistry , lithium (medication) , organic chemistry , medicinal chemistry , ion , medicine , deprotonation , endocrinology

C (α), O ‐Dilithiooximes, C (α), N ‐dilithiophenylhydrazones, or C (α), N ‐dilithioacylhydrazones were prepared in an excess of lithium diisopropylamide (LDA) and condensed with a variety of esters followed by acid‐cyclization to give substituted isoxazoles and pyrazoles.

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