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Synthesis of 4‐substituted 5,6‐diphenylmorpholine‐2,3‐diones with two or three chiral centers
Author(s) -
Alcaide Benito,
LópezMardomingo Carmen,
LópezSáez Berta,
PérezOssorio Rafael,
Plumet Joaquín
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220210
Subject(s) - chemistry , medicinal chemistry , stereochemistry
Chiral α‐aminoalcohols obtained by stereoselective reduction of α‐iminoketones have been condensed with oxalyl chloride to afford 4‐substituted 5,6‐diphenylmorpholine‐2,3‐diones having two or three chiral centers.