Diels‐alder cycloadditions of diene‐substituted  N ‐ethoxycarbonyl‐2‐methyl‐1,2‐dihydropyridines with  N ‐phenylmaleimide | Zendy

Krow Grant R. | Zendy; Can Kevin C. | Zendy; Carey James T. | Zendy; Lee Yoon B. | Zendy; Szczepanski Steven W. | Zendy; Ramjit Harri G. | Zendy

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Diels‐alder cycloadditions of diene‐substituted N ‐ethoxycarbonyl‐2‐methyl‐1,2‐dihydropyridines with N ‐phenylmaleimide

Author(s) -

Krow Grant R.,

Can Kevin C.,

Carey James T.,

Lee Yoon B.,

Szczepanski Steven W.,

Ramjit Harri G.

Publication year - 1985

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570220133

Subject(s) - chemistry , diene , medicinal chemistry , dihydropyridine , alkyl , diels–alder reaction , bicyclic molecule , cycloaddition , organic chemistry , catalysis , calcium , natural rubber

The ten possible substitution patterns for N ‐Ethoxycarbonyl‐2‐methyl‐1,2‐dihydropyridines 5 in which one or two olefinic sites are alkyl substituted were synthesized and reacted with N ‐phenylmaleimide 2 to provide cycloadducts 6. N ‐Ethoxycarbonyl‐5,6‐cyclohexyl‐2‐methyl‐1,2‐dihydropyridine 51 provided the novel spirocycle 61.

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