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Reactions of ethyl β‐methoxycrotonate with some α,β ‐unsaturated carbonyl compounds. Synthesis of 6‐aroyl‐5‐aryl‐3‐methoxycyclohex‐2‐enones
Author(s) -
Shandala Mowafak Y.,
Ayoub Mikdad T.,
Kareem Ahmad A.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210638
Subject(s) - chemistry , aryl , sodium hydride , hydride , medicinal chemistry , nuclear magnetic resonance spectroscopy , organic chemistry , metal , alkyl
3‐Aryl‐1‐phenyl‐2‐propen‐1‐ones Ia‐h and 1‐aryl‐3‐phenyl‐2‐propen‐1‐ones Ii‐ℓreacted with ethyl β‐methoxy‐crotonate (II) in the presence of sodium hydride in dry THF at 0° for 10 hours to give the corresponding 6‐aroyl‐5‐aryl‐3‐methoxy‐2‐cyclohexen‐1‐ones III. The structures of the products were confirmed by ir, pmr, 13 C nmr and uv spectroscopy.