Research Library

Premium Synthesis of pyrazolo[4,3‐ d ]oxazoles
Author(s)
Youssef M. S. K.,
Metwally S. A. M.,
ElMaghraby M. A.,
Younes M. I.
Publication year1984
Publication title
journal of heterocyclic chemistry
Resource typeJournals
PublisherWiley‐Blackwell
Abstract 1‐Phenyl‐3‐methyl‐5‐pyrazolone‐4‐oxime reacted with benzylamine, methylamine, methyl‐ and ethyl ioides to give 3‐methyl‐1,5‐diphenyl‐1 H ‐, 3‐methyl‐1‐phenyl‐1 H ‐ and 3,5‐dimethyl‐1‐phenyl‐1 H ‐pyrazolo[4,3‐ d ]oxazoles I, II. The structure of I was elucidated authentically through other routes by interaction of 1‐phenyl‐3‐methyl‐4,5‐dioxopyrazolone with benzylamine and/or benzaldehyde and ammonium acetate. Various 3‐meth‐yl‐5‐aryl‐1‐phenyl‐1 H ‐pyrazolo[4,3‐ d ]oxazoles IV were synthesized by the reaction of 4,5‐dioxopyrazolone with aromatic aldehydes in the presence of ammonium acetate. Also, the structure of I was elucidated authentically via other routes by the reaction of 1‐phenyl‐3‐methyl‐4‐imino‐5‐pyrazolone with each of benzylcyanide, benzylamine, benzaldehyde and benzalaniline.
Subject(s)alkyl , ammonium acetate , aryl , benzaldehyde , benzylamine , catalysis , chemistry , high performance liquid chromatography , medicinal chemistry , methylamine , organic chemistry , pyrazolone
Language(s)English
SCImago Journal Rank0.321
H-Index59
eISSN1943-5193
pISSN0022-152X
DOI10.1002/jhet.5570210635

Seeing content that should not be on Zendy? Contact us.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here