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Synthesis of 2‐substituted naphtho[1′,2′:4,5]thiazolo[3,2‐ b ]‐1,2,4‐triazoles
Author(s) -
Liu KangChien,
Shih BiJane,
Tao TungMei
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210567
Subject(s) - chemistry , thiazole , amination , salt (chemistry) , base (topology) , medicinal chemistry , stereochemistry , organic chemistry , mathematical analysis , mathematics , catalysis
N ‐Amination of 2‐aminonaphtho[1,2‐ d ]thiazole ( 1 ) with O ‐mesitylenesulfonylhydroxylamine ( 2 ) afforded the corresponding 2,3‐diaminonaphthothiazolium salt 3a . Cyclocondensation of 3a or its free base 3b with appropriate carboxylic acid derivatives 4a‐f gave the title compounds 5a‐f in satisfactory yields (54–95%). Structures of the products were assigned on the bases of spectral and elemental analyses.