Premium
Radical cation formation and crystal structure determination of 4′‐dimethylamino‐10‐phenylpyrido[3,2‐ b ]benzothiazine
Author(s) -
Jovanovic Misa V.,
Biehl Edward R.,
De Meester Patrice,
Chu Shirley S. C.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210540
Subject(s) - chemistry , benzothiazine , ring (chemistry) , aryl , phenothiazine , crystal structure , radical ion , crystallography , group (periodic table) , aryl radical , medicinal chemistry , crystal (programming language) , stereochemistry , photochemistry , organic chemistry , ion , medicine , programming language , alkyl , computer science , pharmacology
The crystal structure of title compound, 4 , shows that the 10‐aryl group is parallel to the plane bisecting the pyridobenzothiazine ring. This structure is in contrast to that normally found for phenothiazines substituted with electron‐withdrawing substituents on the 10‐phenyl ring. In those compounds, the 10‐aryl group is perpendicular to the plane bisecting the phenothiazine ring. The esr spectrum of the cation radical of 4 shows that the radical is located on the hetero ring system which is opposite to that of the cation radical of 4′‐dimethylamino‐10‐phenylphenothiazine in which the radical is located on the 10‐aryl ring.