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Thiazolopyridine analogs of nalidixic acid. 2. Thiazolo[4,5‐ b ]pyridines
Author(s) -
Leysen D. C.,
Haemers A.,
Bollaert W.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210522
Subject(s) - chemistry , nalidixic acid , antibacterial activity , in vitro , pyridine , stereochemistry , medicinal chemistry , organic chemistry , antibiotics , bacteria , biochemistry , antibiotic resistance , biology , genetics
A series of 2‐substituted 4‐ethyl‐4,7‐dihydro‐7‐oxothiazolo[4,5‐ b ]pyridine‐6‐carboxylic acids were synthesized. Antibacterial activity was tested in vitro . None of the new compounds prepared showed any interesting antibacterial activity in vitro against the strains tested.