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Synthesis of the 5 H ‐pyrrolo[2,1‐ a ]isoindole ring with 1,3‐dipolar cycloaddition reactions
Author(s) -
New J. S.,
Yevich J. P.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210521
Subject(s) - isoindole , chemistry , mesoionic , cycloaddition , 1,3 dipolar cycloaddition , ring (chemistry) , acetic anhydride , stereochemistry , medicinal chemistry , organic chemistry , catalysis
The 1,3‐dipolar cycloaddition reaction between mesoionic oxazolines, formed from either 1,3‐dihydro‐2‐substituted‐2 H ‐isoindole‐1‐carboxylic acids or 1,3‐dihydro‐1‐oxo‐α‐substituted‐2 H ‐isoindole‐2‐acetic acids, and dimethylacetylene dicarboxylate has led to the synthesis of several 5 H ‐pyrrolo[2,1‐ a ]isoindole derivatives 9a‐d .
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