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Zur addition von nucleophilen an C(2) heterocyclischer 2‐methylsubstituierter quartärsalze
Author(s) -
Schelz Dieter
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210519
Subject(s) - chemistry , perchlorate , nucleophile , mass spectrum , medicinal chemistry , alkylation , organic chemistry , ion , catalysis
1‐(4‐Chlorophenyl)‐2‐methyl‐3‐phenylquinoxalinium perchlorate ( 5 ) obtained by two different routes, on treating with nucleophiles HX or X − yielded 1,3‐diaryl‐2‐methyl‐2X‐1,2‐dihydroquinoxalines 10 . Alkylation of 10e yielded 4‐(4‐chlorophenyl)‐1,3‐dimethyl‐3‐nitromethyl‐2‐phenyl‐3,4‐dihydroquinoxalinium perchlorate ( 11e ). The 1 H‐nmr and mass spectra are presented. Diastereoisomerism of the products is discussed.