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The synthesis of 1‐substituted 6‐amino‐1 H ‐pyrrolo‐[3,2‐ c ]pyridin‐4(5 H )‐ones
Author(s) -
Schneller Stewart W.,
Luo JiannKuan,
Hosmane Ramachandra S.,
DÚrrfeld Rainer H.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210445
Subject(s) - chemistry , substituent , stereochemistry
The synthesis of 1‐methyl‐ ( 1a ) and 1‐benzyl‐6‐amino‐1 H ‐pyrrolo[3,2‐c]pyridin‐4(5 H )‐one ( 1b ) from the appropriate N ‐alkylaminoacetaldehyde is described. These provide examples of a synthetic procedure that can be used to prepare 1‐substituted 6‐amino‐1 H ‐pyrrolo[3,2‐ c ]pyridin‐4(5 H )‐ones wherein the N‐1 substituent is regiospecifically placed.