Premium
The synthesis of 1‐substituted 6‐amino‐1 H ‐pyrrolo‐[3,2‐ c ]pyridin‐4(5 H )‐ones
Author(s) -
Schneller Stewart W.,
Luo JiannKuan,
Hosmane Ramachandra S.,
DÚrrfeld Rainer H.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210445
Subject(s) - chemistry , substituent , stereochemistry
The synthesis of 1‐methyl‐ ( 1a ) and 1‐benzyl‐6‐amino‐1 H ‐pyrrolo[3,2‐c]pyridin‐4(5 H )‐one ( 1b ) from the appropriate N ‐alkylaminoacetaldehyde is described. These provide examples of a synthetic procedure that can be used to prepare 1‐substituted 6‐amino‐1 H ‐pyrrolo[3,2‐ c ]pyridin‐4(5 H )‐ones wherein the N‐1 substituent is regiospecifically placed.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom