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Synthesis and reactivity of 1‐methyl‐3‐phenyl‐4‐diazo‐5‐benzoylamidopyrazole. A potential antitumor agent
Author(s) -
Cecchi Lucia,
De Sio Francesco,
Melani Fabrizio
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210405
Subject(s) - chemistry , diazo , yield (engineering) , derivative (finance) , methylene , reactivity (psychology) , combinatorial chemistry , stereochemistry , organic chemistry , medicinal chemistry , pathology , economics , financial economics , metallurgy , medicine , materials science , alternative medicine
The title compound 2 was prepared in excellent yield by diazotation of the parent amino derivative. Compound 2 was found to react with a variety of acyclic and cyclic active methylene compounds to yield the corresponding pyrazolo‐4‐ylhydrazones.