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Synthesis of 5,7‐dichloro‐2 H ‐1‐benzopyran‐2‐ol
Author(s) -
Stokker G. E.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210269
Subject(s) - chemistry , cinnamaldehyde , acetonitrile , yield (engineering) , aqueous solution , benzopyran , medicinal chemistry , chloride , organic chemistry , catalysis , materials science , metallurgy
The reaction of 4,6‐dichloro‐2‐(methylthiomethoxy)cinnamaldehyde ( 3 ) or 4,6‐dichloro‐2‐hydroxycinnamaldehyde ( 5 ) with mercuric chloride in hot aqueous acetonitrile gave 5,7‐dichloro‐2 H ‐1‐benzyopyran‐2‐ol ( 4 ) in good yield.