Synthesis of 3,5‐disubstituted 1,3,4‐oxadiazole‐2‐thiones as potential fungicidal agents | Zendy

Goswami B. N. | Zendy; Kataky J. C. S. | Zendy; Baruah J. N. | Zendy; Nath S. C. | Zendy

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Synthesis of 3,5‐disubstituted 1,3,4‐oxadiazole‐2‐thiones as potential fungicidal agents

Author(s) -

Goswami B. N.,

Kataky J. C. S.,

Baruah J. N.,

Nath S. C.

Publication year - 1984

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570210141

Subject(s) - chemistry , oxadiazole , alkyl , proton nmr , aryl , mass spectrum , elemental analysis , organic chemistry , medicinal chemistry , fungicide , carbon 13 nmr , botany , ion , biology

Sixteen new 3‐arylaminomethyl‐5‐(2,4‐dichlorophenyl)‐1,3,4‐oxadiazole‐2‐thione and six 3‐alkyl aryl alkyl‐5‐(2,4‐dichlorophenyl)‐1,3,4‐oxadiazole‐2‐thiones were synthesised and characterised by their sharp melting points, elemental analysis, ir, 1 H nmr and mass spectra. These substituted oxadiazolethiones were screened for their fungitoxic properties. Most of the compounds showed toxicity against two test organisms, Curvularia verruciformis and Alternaria tenuis . The degree of inhibition ranged from 38‐‐100% for a few compounds.

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