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Derivatives of benzo[4,5]cyclohepta[1,2‐ b ]thiophene. 1 . Synthesis and cyclization of N ‐(9,10‐dihydro‐4 H ‐benzo[4,5]cyclohepta‐[1,2‐‐6]thiophene‐4‐ylmethyl)amides
Author(s) -
Arribas Enrique,
Vega Salvador
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210132
Subject(s) - chemistry , thiophene , ketone , intramolecular force , stereochemistry , medicinal chemistry , organic chemistry
Starting from ketone III several acyl derivatives of 4‐aminomethyl‐9,10‐dihydro‐4 H ‐benzo[4,5]cyclohepta‐[1,2‐‐6]thiophene (VII) have been synthesized. The intramolecular cyclization of some of these new amides through the Bischler‐Napieralski reaction is described.