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bis‐alkylsulfonylpyridines
Author(s) -
Woods S. G.,
Matyas B. T.,
Vinogradoff A. P.,
Tong Y. C.
Publication year - 1984
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570210121
Subject(s) - chemistry , decarboxylation , hydrolysis , sodium , medicinal chemistry , group (periodic table) , organic chemistry , nitrile , catalysis
Dihalogenated pyridines, some activated with carboxylic, ester or cyano group, were allowed to react with sodium alkylmercaptides. After hydrolysis of the ester or cyano group followed by decarboxylation, bis‐alkylthiopyridines with substituents at 2,3‐, 2,4‐, 2,5‐, 2,6‐ and 3,5‐positions were prepared. These compounds were oxidized to bis‐alkylsulfonylpyridines.