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Oxidation reactions of indapamide. A novel route to the indole derivative, N ‐(3‐sulfamyl‐4‐chlorobenzamido)‐2‐methylindole
Author(s) -
O'Hare M. J.,
Tan E.,
Rehm C.,
Grebow P.,
Loev B.,
Neiss E.
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200365
Subject(s) - indole test , indapamide , chemistry , oxidizing agent , dehydrogenation , derivative (finance) , combinatorial chemistry , medicinal chemistry , organic chemistry , pharmacology , catalysis , diuretic , medicine , financial economics , economics
Indapamide ( 1 ) is readily oxidized with mild oxidizing agents to the indole derivative 2 . Dehydrogenation of indapamide is a convenient one step synthesis of a complex indole compound.