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Synthesis of (1‐substituted piperidin‐4‐yl)‐1 H ‐benzimidazoles and (1‐substituted piperidin‐4‐yl)‐3,4‐dihydroquinazolines as possible antihypertensive agents
Author(s) -
Obase Hiroyuki,
Takai Haruki,
Teranishi Masayuki,
Nakamizo Nobuhiro
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200315
Subject(s) - chemistry , combinatorial chemistry , alkoxy group , stereochemistry , medicinal chemistry , organic chemistry , alkyl
Structural modifications of 4‐piperidylbenzimidazolinones (I) by replacing the benzimidazolinone group with other heterocycles (2‐cyanoamino, 2‐ethoxy, and 2‐methylbenzimidazole and 2‐cyanoamino‐3,4‐dihydroquinazoline) has been made and a number of new piperidines (II) were synthesized as potential antihypertensive agents.