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Synthesis and some reactions of hexahydro‐1,2,4‐triazine‐3,6‐dione
Author(s) -
Schwan Thomas J.
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200312
Subject(s) - chemistry , hydrogenolysis , triazine , ring (chemistry) , 1,3,5 triazine , medicinal chemistry , stereochemistry , organic chemistry , catalysis
The synthesis of hexahydro‐1,2,4‐triazine‐3,6‐dione by hydrogenolysis of 1,2‐dibenzylhexahydro‐1,2,4‐triazine‐3,6‐dione is reported. Ring contraction of the former dione to 3‐amino‐2,4‐imidazolidinedione is discussed. The preparation of the 1‐ and 2‐benzyl derivatives of hexahydro‐1,2,4‐triazine‐3,6‐dione and their conversion to the unsubstituted product are also described.