Synthesis of some 5,6,7,8‐tetrahydro‐4‐cinnolone derivatives and 1‐methyl‐3‐arylacetyl‐4,5,6,7‐tetrahydroindazoles | Zendy

Gelin Suzanne | Zendy; Dolmazon René | Zendy

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Synthesis of some 5,6,7,8‐tetrahydro‐4‐cinnolone derivatives and 1‐methyl‐3‐arylacetyl‐4,5,6,7‐tetrahydroindazoles

Author(s) -

Gelin Suzanne,

Dolmazon René

Publication year - 1983

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570200311

Subject(s) - chemistry , mesoionic , methylhydrazine , hydrazine (antidepressant) , hydrate , medicinal chemistry , methylation , organic chemistry , demethylation , stereochemistry , phenylhydrazine , biochemistry , gene expression , chromatography , dna methylation , gene

2‐Arylidene‐3‐oxo‐2,3,4,5,6,7‐hexahydrobenzo[ b ]furans 2 react with hydrazine hydrate to afford 5,6,7,8‐tetrahydro‐4‐cinnolones. By methylation, these compounds gave the corresponding N‐1 and N‐2 methyl derivatives. The mesoionic compounds are obtained, accompanied by 3‐arylacetyl‐4,5,6,7‐tetrahydroindazoles upon reaction of 2 with methylhydrazine.

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