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Synthesis of 1 H ,3 H ‐imidazo[1,5‐ c ]thiazole‐5,7‐[6 H ,7a H ]‐dione and 7,8‐dihydro‐5‐ H ‐imidazo[1,5‐ c ][1,3]thiazine‐1,3‐[2 H ,8a H ]‐dione and derivatives
Author(s) -
Lalezari I.,
Seifter S.,
Thein A.
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200247
Subject(s) - chemistry , thiazole , thiazine , bicyclic molecule , thiolactone , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry
1 H ,3 H ‐Imidazo[1,5‐ c ]thiazole‐5,7‐[6 H ,7a H ]‐dione and the corresponding 7‐thione derivatives as well as 7,8‐dihydro‐5 H ‐imidazo[1,5‐ c ][1,3]thiazine‐1,3‐[2 H ,8a H ]‐dione and the corresponding 3‐thione derivatives were synthesized starting from L ‐cysteine and DL ‐homocysteine thiolactone, respectively. The second group of bicyclic compounds represents a new heterocyclic ring system. The structures of the compounds were confirmed by spectroscopic studies and elemental analyses.