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A short regiospecific total synthesis of furoventalene, a marine natural benzofuran
Author(s) -
Bergstrom Donald E.,
Reddy P. Anantha
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200242
Subject(s) - chemistry , benzofuran , yield (engineering) , total synthesis , bromide , organic chemistry , terpenoid , catalysis , combinatorial chemistry , stereochemistry , materials science , metallurgy
Synthesis of a naturally occurring irregular isoprenoid benzofuran, furoventalene ( 3 ), has been achieved in high yield via the nickel catalyzed coupling of 4‐methyl‐3‐penten‐1‐ylmagnesium bromide ( 1 ) with 3‐methyl‐6‐chlorobenzofuran ( 2 ).