Tetraoxo derivatives of perhydropyrrolo[3,4‐ c ]pyridine | Zendy

Ferappi M. | Zendy; Carotti A. | Zendy; Casini G. | Zendy; De Laurentis N. | Zendy; Giardinà D. | Zendy; Cingolani G. M. | Zendy; Gavuzzo E. | Zendy; Mazza F. | Zendy

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Tetraoxo derivatives of perhydropyrrolo[3,4‐ c ]pyridine

Author(s) -

Ferappi M.,

Carotti A.,

Casini G.,

De Laurentis N.,

Giardinà D.,

Cingolani G. M.,

Gavuzzo E.,

Mazza F.

Publication year - 1983

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570200233

Subject(s) - chemistry , succinimide , pyridine , ring (chemistry) , adduct , closure (psychology) , crystal structure , medicinal chemistry , stereochemistry , organic chemistry , economics , market economy

Michael adducts from diethyl fumarate with malonic esters or nitriles were cyclized to succinimide intermediates which, after glutarimide ring closure, afforded several N ‐methyl and N ‐benzyl derivatives of cis ‐1,3,4,6‐tetraoxoperhydropyrrolo[3,4‐ c ]pyridine whose configuration was demonstrated by X‐ray crystal structure analysis.

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