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Benzoxazol‐2 (3 H )‐one and 1,3,4‐oxadiazol‐2(3 H ) ‐one derivatives from substituted enaminones and ketoenamines
Author(s) -
Forchiassin M.,
Pitacco G.,
Risaliti A.,
Russo C.,
Valentin E.
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200210
Subject(s) - chemistry , hydrazine (antidepressant) , substituent , medicinal chemistry , stereochemistry , chromatography
Enaminones and ketoenamines bearing a hydrazine type substituent undergo side chain thermal cyclization, the former into benzoxazol‐2 (3 H )‐one derivatives and the latter into 1, 3, 4‐oxadiazol‐2 (3 H )‐one derivatives. Factors affecting such reactions are discussed.