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Synthesis and mass spectral fragmentation of 2‐methylthio‐7‐( p ‐R‐phenyl)‐8‐phenoxy‐4,5‐benzo‐3‐aza‐2‐nonem. III
Author(s) -
Cortés E.,
Martínez R.
Publication year - 1983
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570200134
Subject(s) - chemistry , fragmentation (computing) , ion , mass spectrum , electron ionization , polyatomic ion , cycloaddition , stereochemistry , molecule , proton nmr , medicinal chemistry , organic chemistry , ionization , computer science , catalysis , operating system
A series of new 2‐methylthio‐7‐( p ‐R‐phenyl)‐8‐phenoxy‐4,5‐benzo‐3‐aza‐2‐nonem, IIIa, have been synthesized by regiospecific cycloaddition of phenoxyacetyl on to 2‐methylthio‐4‐( p ‐ R ‐phenyl)‐3 H ‐1,5‐benzodiazepines IV. The structure was established by ir, 1 H‐nmr and ms spectral data together with 13 C‐nmr spectral data of desulfurization products, VIa. Likewise, a study has been made of the fragmentation upon electron impact of IIIa and IV. All the spectra analyzed contain molecular ions and the principal fragmentation routes takes place either from the molecular ion or from m/e (M + — 134) ion. This ion is the base peak for all the compounds analyzed.