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Polycyclic nitrogen compounds. Part I. Synthesis of new heterotricyclic quinoxalinones with bridgehead nitrogen atoms
Author(s) -
Adegoke E. A.,
Alo Babajide I.,
Ogunsulire F. O.
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190536
Subject(s) - chemistry , pyrrolidine , piperidine , tricyclic , nitrogen , ring (chemistry) , carboxylic acid , medicinal chemistry , stereochemistry , organic chemistry
New tricyclic quinoxalinone skeletons with a fully‐reduced ring ‘C’ ‐1,2,3,3a‐tetrahydropyrrolo[1,2‐α]quin‐oxalin‐4‐one (I‐II) and 7,8,9,10‐tetrahydropyrido[1,2‐α]quinoxalin‐6‐one (III‐IV) derivatives were obtained by selective hydrogen transfer reductive cyclisation of N ‐(2‐nitrophenyl)pyrrolidine‐2‐carboxylic acid esters and N ‐(2‐nitrophenyl)piperidine‐2‐carboxylic acid esters (VIa,b and VIIIa,b), respectively.

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