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The synthesis of macrocyclic polyether‐diesters incorporating 1,10‐phenanthrolino and 1,8‐naphthyridino subunits
Author(s) -
Chandler Christopher J.,
Deady Leslie W.,
Reiss James A.,
Tzimos Vasilios
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190507
Subject(s) - chemistry , chloride , phenanthroline , medicinal chemistry , combinatorial chemistry , polymer chemistry , stereochemistry , organic chemistry
The preparation of a series of macrocycles, formed by reaction of HO‐(‐CH 2 ‐CH 2 ‐O‐) n H with 1,10‐phenanthroline‐2,9‐dicarbonyl chloride (n = 2,3,4) and 1,8‐naphthyridine‐2,7‐dicarbonyl chloride (n = 3,4), is described. An improved synthetic route to 2,7‐dimethyl‐1,8‐naphthyridine 9 is also reported.