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Reaction of indol‐3(2 H )‐one derivatives with some active methylene compounds
Author(s) -
Daisley Roy W.,
Elagbar Zaha A.,
Walker John
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190506
Subject(s) - malononitrile , chemistry , methylene , cyanoacetic acid , ethyl cyanoacetate , indole test , organic chemistry , molecule , medicinal chemistry , catalysis
The reaction of substituted ( Z )‐ and ( E )‐2‐arylmethylideneindolin‐3(2 H )‐ones with malononitrile gave the Micheal addition products which could be cyclised to the corresponding pyrano[3,2‐ b ]indole. Larger molecules such as cyanoacetic acid and ethyl cyanoacetate failed to react.