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Base‐promoted cyclization of 1‐nitrohydrazones bearing a thioether function
Author(s) -
Bruché Luca,
Garanti Luisa,
Zecchi Gaetano
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190438
Subject(s) - chemistry , thioether , nitrile , boiling , bearing (navigation) , sodium hydride , benzene , ring (chemistry) , base (topology) , hydride , function (biology) , medicinal chemistry , organic chemistry , mathematical analysis , cartography , mathematics , geography , evolutionary biology , biology , hydrogen
Functionalized 1‐nitrohydrazones 5 react with sodium hydride in boiling benzene to afford different types of ring‐closed products. The formation of the latter can be ascribed to competitive modes of evolution of first‐formed nitrile imines.