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Two syntheses of 5‐chloro‐3‐(2‐thienyl)‐2,1‐benzisoxazole
Author(s) -
Klemm L. H.,
Klopfenstein C. E.,
Nelson Steven K.
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190348
Subject(s) - chemistry , thiophene , hydrochloric acid , condensation , organic chemistry , medicinal chemistry , spectral properties , computational chemistry , thermodynamics , physics
5‐Chloro‐3‐(2‐thienyl)‐2,1‐benzisoxazole ( 2 ) resulted from condensation of (a) o ‐nitrobenzaldehyde with thiophene in the presence of hydrochloric acid and (b) p ‐chloronitrobenzene with 2‐cyanomethylthiophene. Spectral data for ( 2 ) are presented and interpreted.