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The synthesis of 8‐azidoadenine, a photoaffinity labeling agent
Author(s) -
Marburg S.,
Jorn D.,
Tolman R. L.
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190346
Subject(s) - chemistry , photoaffinity labeling , cleavage (geology) , yield (engineering) , homogeneous , hydrolysis , combinatorial chemistry , stereochemistry , organic chemistry , binding site , biochemistry , materials science , physics , geotechnical engineering , fracture (geology) , engineering , metallurgy , thermodynamics
The photoaffinity labeling agent, 8‐azidoadenine, was prepared in good yield by hydrolytic cleavage of 8‐azidoadenosine and characterized as a homogeneous compound. Previously reported physical data for this compound was shown to be in accord with mixtures of 8‐azido‐ and 8‐bromoadenine.