5‐Bromobenzofuran Analog of Chloramphenicol | Zendy

Bevinakatti Hanamanthsa S. | Zendy; Badiger Virupax V. | Zendy

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5‐Bromobenzofuran Analog of Chloramphenicol

Author(s) -

Bevinakatti Hanamanthsa S.,

Badiger Virupax V.

Publication year - 1982

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570190111

Subject(s) - chemistry , fragmentation (computing) , propane , diol , chloramphenicol , medicinal chemistry , stereochemistry , organic chemistry , antibiotics , biochemistry , computer science , operating system

dl‐threo ‐2‐Dichloroacetamido‐1‐[2‐(5‐bromobenzofuranyl)] propane‐1, 3‐diol ( 7 ) was synthesised according to Sorm's method. The fragmentation of 2‐dichloroacetamido‐3‐hydroxy‐1‐[2‐(5‐bromobenzofuranyl)[‐1‐propanone ( 6 ) under electron impact is reported. The base peak is due to the rupture of the central bond whereas loss of water and McLafferty rearrangement also lead to important fragmentation pathways.

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