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Rearrangement of 3‐arylhydantoins into 3‐aminoglycocyamidines
Author(s) -
Daboun Hamed A.,
Ibrahim Yehia A.
Publication year - 1982
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570190105
Subject(s) - chemistry , hydrate , hydrazine (antidepressant) , aryl , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry , alkyl , chromatography
The action of hydrazine hydrate on 5‐arylidene‐3‐aryl‐2‐methylmercaptohydantoins led to ring opening and rearrangement into 5‐arylidene‐3‐amino‐ N 2 ‐aryl‐glycocyamidines ( 9a‐f ). The structure of the products 9a‐f was established and the mechanism of their formation was discussed.