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Syntheses of some hydroxylated metabolites of psychotropic trifluoromethyl analogs of chlorpromazine
Author(s) -
Nodiff E. A.,
Sharma H. L.,
Taunk P. C.,
Shukla A. P.,
Sadhnani M. D.,
Tambi S. B.,
Mital R. L.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180807
Subject(s) - trifluoperazine , chemistry , chlorpromazine , fluphenazine , trifluoromethyl , phenothiazine , pharmacology , organic chemistry , enzyme , psychology , haloperidol , dopamine , medicine , neuroscience , calmodulin , alkyl
The syntheses of 7‐hydroxy derivatives of trifluoperazine, nor,‐trifluoperazine, fluphenazine, triflupromazine and nor,‐triflupromazine are described. These were prepared as analytical standards for the identification of these metabolites in biological materials.