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Synthesis of bridgeheaded nitrogen systems. s ‐triazolo[4,3‐ b ]‐ as ‐triazine, s ‐triazolo[4,3‐ d ]‐ as ‐triazine and s ‐triazolo[3,4‐ b ]‐1,3,4‐Thiadiazole ring systems
Author(s) -
Sasaki Tadashi,
Ito Eikoh
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180716
Subject(s) - chemistry , thiadiazoles , cyanogen bromide , triazine , bromide , nitrogen , medicinal chemistry , cyanogen , stereochemistry , organic chemistry , biochemistry , peptide sequence , gene
By the reactions of hydrazino‐ as ‐triazines ( 1a‐d and 5 ) with cyanogen bromide were synthesized s ‐triazolo‐ as ‐triazines ( 2a‐d ) and ( 6 ). Likewise, similar reactions of amino‐ s ‐triazolethiols ( 7a‐e ) gave s ‐triazolo‐1,3,4‐thiadiazoles ( 8a‐e ). Compound 2a was brominated to 2g.