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Synthesis of N,N' ‐Diacyl‐1,2‐di‐(4‐pyridyl)ethylenedianiines
Author(s) -
Braña M. F.,
Rodriguez Maria L. López,
Garrido J.,
Roldán C. M.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180707
Subject(s) - chemistry , benzamide , pyridine , acetic anhydride , ring (chemistry) , medicinal chemistry , nitrogen atom , analgesic , analgesic agents , stereochemistry , organic chemistry , catalysis , medicine , pharmacology
Reaction of N ‐(4‐pyridylmethyl)benzamide N ‐oxides with acetic anhydride yielded dimerization compounds. This dimerization occurs at the atom attached to the pyridine ring. These compounds so obtained were evaluated for analgesic and antiinflammatory activity.