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1,3‐dipolar addition of pyridine N ‐imine to acetylenes and the use of C‐13 NMR in several structural assignments
Author(s) -
Anderson Paul L.,
Hasak James P.,
Kahle Alicia D.,
Paolella Nicholas A.,
Shapiro Michael J.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180617
Subject(s) - chemistry , imine , pyridine , medicinal chemistry , organic chemistry , carbon 13 nmr , catalysis
Addition of pyridine‐ N ‐imine to a variety of acetylenic mono‐ (Scheme I) and di‐ (Scheme II) carboxylic ester dipolarophiles was carried out. Several of the 3‐azapyrrocoline esters obtained were further converted into acids, amides and hydrazides as shown in Schemes I and II.