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1,2,4‐Triazines. II. A new general synthesis of 3,4‐dihydro‐1,2,4‐triazin‐5‐(2 H )ones
Author(s) -
Sanemitsu Yuzuru,
Nakayama Yoskinori,
Shiroshita Masao
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180539
Subject(s) - chemistry , sodium borohydride , dimethylformamide , combinatorial chemistry , reduction (mathematics) , medicinal chemistry , organic chemistry , catalysis , geometry , mathematics , solvent
3,4‐Dihydro‐1,2,4‐triazin‐5‐(2 H )ones were prepared by the reduction of 3‐methylthio‐1,2,4‐triazin‐5‐(2 H )‐ones with sodium borohydride in dimethylformamide. The synthesis appears to be general.