Premium
Facile deacylation of N ‐acyl‐2,3‐dihydrobenzo‐1,4‐thiazine 1‐oxide and 1,1 dioxide
Author(s) -
Florio Saverio,
Leng John L.,
Stirling Charles J. M.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180452
Subject(s) - chemistry , thiazine , oxide , organic chemistry , medicinal chemistry
The title amides react easily with methanolic sodium methoxide at room temperature affording 2,3‐dihydrobenzo‐1,4‐thiazine 1‐oxide and 1,1‐dioxide and methylacetate. An unusual mechanism of deacylation is proposed.