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Studies on the synthesis of heterocyclic compounds. Part VI. The action of methyl salicylate on some 5‐aminopyrazoles
Author(s) -
Daidone Giuseppe,
Plescia Salvatore
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180422
Subject(s) - chemistry , methyl salicylate , hydrolysis , medicinal chemistry , organic chemistry , stereochemistry , ecology , biology
Some 1‐phenyl‐3‐ R ‐5‐aminopyrazoles reacted with methyl salicylate to give N ‐(1‐phenyl‐3‐ R ‐pyrazol‐5‐yl)‐2‐methoxybenzamides ( 3a,b,c ), 1‐phenyl‐2‐methyl‐3‐ R ‐salicyloilimino‐3‐pyrazolines ( 4a,b,c ) together with 1‐phenyl‐3‐ R ‐5‐methylamino pyrazoles ( 5a,b,c ). The structures of the new compounds 3 and 4 were determined on the basis of analytical and spectroscopic data as well as on the acid hydrolysis products.