Premium
Pyrazoles. XVIII . Synthesis of a novel tripyrazolyl by two consecutive cine substitution reactions
Author(s) -
Berbee Robertas P. M.,
Habraken Clarisse L.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180324
Subject(s) - chemistry , pyrazole , substitution (logic) , solvent , nucleophilic substitution , substitution reaction , medicinal chemistry , nitro , organic chemistry , alkyl , computer science , programming language
Preparation of the C‐N coupled tripyrazolyl VII, by two consecutive cine substitution reactions starting from 1,4‐dinitropyrazole and using pyrazole as a nucleophile, is described. Solvent dependent nitrations of 4‐nitro‐3(5)‐(1′‐pyrazolyl)pyrazole I are reported.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom