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Amidrazones. 6 . Synthesis of 1,2,4‐thiadiazoles by thermolysis of N 3 ‐thiocarbamoylamidrazone ylides
Author(s) -
Smith Richard F.,
Feltz Timothy P.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180140
Subject(s) - thiadiazoles , chemistry , thermal decomposition , alkyl , aryl , medicinal chemistry , decomposition , organic chemistry
Reaction of N 3 ‐unsubstituted amidrazone ylides ( 1a and 1b ) with alkyl or aryl isothiocyanates gives N 3 ‐thiocarbamoylamidrazone ylides ( 2 ). Thermolysis of 2 gives 3‐alkyl(or aryl)‐5‐alkyl(or aryl)amino‐1,2,4‐thiadiazoles ( 3a‐i ).
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