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A new synthesis of 6‐(alkyl)amino‐3‐aryl(alkyl)‐1,2,4,5‐tetrazines
Author(s) -
CounottePotman Anda,
Van Der Plas Henk C.
Publication year - 1981
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570180125
Subject(s) - chemistry , alkyl , aryl , potassium permanganate , amine gas treating , organic chemistry , liquid ammonia , ammonia
A new method for the preparation of 6‐(alkyl)amino‐3‐aryl(alkyl)‐1,2,4,5‐tetrazines is described. Dissolving 3‐aryl(alkyl)‐1,2,4,5‐tetrazines in liquid ammonia or a primary aliphatic amine at −35° to −40°, followed by addition of potassium permanganate gives the title compounds in reasonable to excellent yields.